Principal Investigator and Supervising Professor: Dr. Peter Urbanellis, MD, MSc, UHN Multi-Organ Transplant Program
There is currently little knowledge of the experiences and service needs of the Lesbian, Gay, Bisexual, Trans, and Queer (LGBTQ+) community internationally. Research indicates that LGBTQ+ communities are often at greater risk of violence and discrimination which may also lead to greater mental health problems, suicidal ideation, internalized homophobia, and abuse resulting from the use of online dating applications. Due to this, they often have greater needs for safe services, community support, and protection against this higher risk of harms. This project includes data from the MSc Thesis Data of Raymond M. McKie and data from the OutLook Study.
Supervisor and Principal Investigator: Raymond M. McKie, MSc, Ph.D. candidate and Dr. Robert N. Travers, Ph.D.
Funding: Faculty of Science Students’ Association (FOSSA)
Supervising Professor and Principal Investigator: Dr. Shlomit Kenigsberg, Ph.D., MBA and Dr. Clifford L. Librach, MD, FRSC(C), FACOG(REI)
Funding: Sunnybrook Research Institute Davis + Henderson Student Research Award & CReATe Fertility Centre
The M-Domain of TOC complexes, specifically TOC159M, remains a mystery to this day. Understanding how this protein can be expressed in various organisms including that of Escherichia coli is consequential in understanding how TOC159M, a membrane protein, interacts with bacterial membranes. According to Zoonens and Miroux, the so-called internal membrane is also produced when auto-inducing a culture of BL-21 Codon Plus (RIPL) E.coli. The main goal of Prem’s research project is to further understand the expression of protein in membranes, the role of the internal membranes and how they are produced, and analyze the M-domain to determine structure and function. Various methods include auto-induction, IMAC purification, in addition to assays including Bradford, NADH oxidase, BCA, and lipid to determine solubility of the protein in different detergents with an end goal of determining the structure and function of the atTOC159 M-domain.
Principal Investigator and Supervising Professor: Dr. Matthew D. Smith, Ph.D., Wilfrid Laurier University
Mentor: Tuan (Patrick) Hoang, MD Candidate, Ph.D., M.Sc.
Funding: Natural Sciences and Engineering Research Council of Canada (NSERC) Undergraduate Student Research Award (USRA) & NSERC Research Discovery Grant (Awarded to Dr. Matthew D. Smith)